“Suddenly, my body won’t move like it used to…”
This mock case collection focuses on patients presenting with motor weakness or paralysis. Each case includes realistic dialogue, diagnostic thinking, and common pitfalls for learners. Practice asking targeted questions and explaining findings in clear English.
- Case 1 – I woke up and couldn’t move my right arm.
- Case 2 – I can’t move my eyes… and now I feel unsteady.
- Case 3 – I must’ve slept funny… now I can’t extend my wrist.
Case 1 – “I woke up and couldn’t move my right arm.”
Doorway Information
- Age / Gender: 71-year-old male
- Chief Complaint: Sudden right-sided weakness
- Vital Signs: T 36.8°C, HR 86, BP 172/96, RR 18, SpO₂ 98% RA
Structured History
Opening: “Yeah… I woke up and just couldn’t move my whole right side.”
Onset & Course: Sudden onset this morning. No trauma. Collapsed when trying to stand.
Associated Symptoms: Slurred speech, imbalance, no headache or vision changes.
Mood / Function / Appetite / Sleep: Scared, otherwise baseline normal.
Medical History: Hypertension (non-compliant), no diabetes or stroke history.
Social History: Smokes 1 pack/day × 40 yrs. Retired, lives alone. No alcohol/drugs.
Concerns: “Is this a stroke? Will I be paralyzed forever?”
Physical Examination
- Right facial droop (lower face)
- Right arm and leg weakness (3/5), pronator drift positive
- Increased reflexes on right
- NIHSS = 6
Differential Diagnosis
- Ischemic stroke (MCA) – sudden focal deficit, HTN, smoking
- Intracerebral hemorrhage – possible, but no headache or vomiting
- Todd’s paralysis – no seizure activity
Clinical Reflection
The presentation was highly suggestive of MCA infarct. Vascular risk factors and neurological deficits supported this.
Clinical Pearls
- 🧠 “Time is brain” – act fast
- 🚬 HTN and smoking = big risk factors
- 🧪 Normal early CT doesn’t rule out stroke
- ✋ Facial + arm + speech = classic triad
Challenging Questions
Q: “Will I recover full movement?”
A: “We’ll do everything we can to help with recovery. Some patients improve a lot with rehab, while others may have lasting weakness. We’ll monitor closely and start therapy early.”
Q: “Can I get treatment to reverse this?”
A: “There are treatments like tPA that can help if given within a few hours. That’s why it’s so important we act fast. We’ll check your scans and labs right away.”
SOAP Note
S: 71M with sudden right hemiparesis and slurred speech upon waking. No headache, no seizure, no trauma. O: T 36.8, HR 86, BP 172/96. Right-sided weakness 3/5, facial droop, increased reflexes. A: # Right-sided weakness # Dysarthria # Vascular risk (HTN, smoking) ddx): MCA stroke, ICH, Todd's paralysis → MCA infarct likely. Urgent CT and neuro consult. P: - CT head - Labs (CBC, BMP, PT/INR, glucose) - Monitor vitals, neuro status
Case 2 – “I can’t move my eyes… and now I feel unsteady.”
Doorway Information
- Age / Gender: 29-year-old male
- Chief Complaint: Double vision and trouble walking
- Vital Signs: T 36.9°C, HR 78, BP 120/76, RR 16, SpO₂ 99% RA
Structured History
Opening: “I can’t move my eyes right. I feel dizzy and can’t walk straight.”
Onset & Course: Gradual over 2 days. Had flu-like illness 1 week ago (fever, sore throat).
Associated Symptoms: Ataxia, perioral numbness, diplopia. No limb weakness.
Medical History: Healthy, no meds.
Social History: Works in tech, social drinker, no drugs.
Concerns: “Could this be MS or a brain tumor?”
Physical Examination
- Ophthalmoplegia (lateral gaze limited)
- Ataxic gait
- Areflexia
- Normal strength and sensation
Differential Diagnosis
- Miller-Fisher syndrome – classic triad + post-viral course
- Cerebellar stroke/tumor – less likely, reflexes preserved
- Myasthenia gravis – unlikely: no ptosis, reflexes normal
Clinical Reflection
The triad and post-infectious course pointed clearly to MFS. We’ll confirm with anti-GQ1b antibodies and LP.
Clinical Pearls
- 👁️ Ophthalmoplegia + ataxia + areflexia = MFS
- 🦠 Usually post-viral (e.g. flu, GI)
- 🧪 Anti-GQ1b positive in >90%
Challenging Questions
Q: “Is this a type of stroke?”
A: “It shares some features, but your symptoms developed gradually and your reflexes are absent, which points to a nerve-related cause. We’ll do scans and blood tests to make sure.”
Q: “Will I get better?”
A: “Most patients recover well with supportive care or immunotherapy. You may need close monitoring for breathing and walking, but recovery is very likely.”
SOAP Note
S: 29M with diplopia and ataxia post-viral illness. No weakness. O: Ophthalmoplegia, ataxia, areflexia. Normal strength. A: # Ophthalmoplegia + ataxia + areflexia # Post-viral course → Miller-Fisher likely. Rule out stroke. P: - MRI - Anti-GQ1b Ab, LP - Monitor FVC - Neuro referral
Case 3 – “I must’ve slept funny… now I can’t extend my wrist.”
Doorway Information
- Age / Gender: 33-year-old male
- Chief Complaint: Wrist drop after sleeping
- Vital Signs: T 36.7°C, HR 72, BP 126/84, RR 16, SpO₂ 99% RA
Structured History
Opening: “I woke up and couldn’t lift my wrist.”
Onset & Course: After clubbing, fell asleep on couch with arm under woman’s body. Woke up with wrist drop.
Associated Symptoms: Dorsal hand numbness. No pain. Normal finger strength.
Medical/Social History: Healthy, no meds. IT job. Drinks socially. No drugs.
Concerns: “Did I damage my nerves forever?”
Physical Examination
- Wrist extensor weakness (wrist drop)
- Normal triceps reflex
- Sensory loss dorsum hand
Differential Diagnosis
- Radial nerve palsy – compression + wrist drop
- Cervical disc herniation – less likely: no neck pain
- Peripheral neuropathy – no systemic cause
Clinical Reflection
Textbook case of compressive radial neuropathy after intoxication and poor posture.
Clinical Pearls
- 🛋️ “Saturday night palsy” = radial nerve compression
- 🍷 Alcohol + posture = risk
- 🧠 Triceps spared → distal lesion
Challenging Questions
Q: “Is this permanent?”
A: “It’s most likely temporary. The nerve got compressed, and it can take a few weeks to fully recover. We’ll monitor and may recommend physical therapy.”
Q: “Do I need an MRI?”
A: “Not right now. Based on your exam and history, this looks like a common nerve compression. If you don’t improve, we’ll reconsider imaging later.”
SOAP Note
S: 33M with wrist drop after sleeping on arm. No trauma. O: Weak wrist extensors, sensory loss dorsum hand. Reflexes intact. A: # Radial nerve palsy (compression) → Saturday night palsy. Conservative management. P: - Reassure - Wrist splint - PT/OT - Recheck in 2 weeks
🔗 Related Articles
- 🧠 “Why Can’t I Move My Arm?” — A Family Doctor’s Guide to Diagnosing Motor Paralysis
- 🧠【症候別アプローチ:運動麻痺 】
- 📘 🩺 Mock Patient Scripts
📚 References
- Harrison’s Principles of Internal Medicine, 21st Edition – Chapter on Neuromuscular Disorders.
- UpToDate: Overview of acute ischemic stroke, Miller Fisher syndrome, and peripheral nerve syndromes.
- American Stroke Association. 2023 Guidelines for the Early Management of Patients With Acute Ischemic Stroke.
- National Institute of Neurological Disorders and Stroke. Miller Fisher Syndrome Fact Sheet.
- BMJ Best Practice. Radial nerve palsy – diagnosis and management.
📘 Recommended Resources – 臨床推論・医療英語の力を深めたい方へ
- First Aid for the USMLE Step 2 CS(英語) – 問診・身体診察・患者対応の定番バイブル。
- ダ・ヴィンチのカルテ(日本語) – 鑑別診断力を鍛える、読み物としても優れた99症例。
- ティアニー先生の臨床入門(日本語) – 初学者から臨床医まで、診察・判断の基本がわかる名著。
- Symptom to Diagnosis: An Evidence-Based Guide – システマティックに鑑別を組み立てる力がつく米国式教科書。
- Clinical Reasoning in General Practice(英語) – GP・家庭医志望に必須の推論スキル解説。
- 診察と手技がみえる Vol.1〜3 – 手技だけでなく、視診・触診の意味を丁寧に解説(図解多数)。
📚 これらの教材は、本記事のような模擬症例学習と組み合わせることで、より深い理解と臨床力の定着につながります。
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